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RNA m(6) A modification enzymes shape innate responses to DNA by regulating interferon β
Modification of mRNA by N(6)-adenosine methylation (m(6)A) on internal bases influences gene expression in eukaryotes. How the dynamic genome-wide landscape of m(6)A-modified mRNAs impacts virus infection and host immune responses remains poorly understood. Here, we show that type I interferon (IFN)...
Autores principales: | Rubio, Rosa M., Depledge, Daniel P., Bianco, Christopher, Thompson, Letitia, Mohr, Ian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295168/ https://www.ncbi.nlm.nih.gov/pubmed/30463905 http://dx.doi.org/10.1101/gad.319475.118 |
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