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Short-Term Environmental Stimulation Spatiotemporally Modulates Specific Serotonin Receptor Gene Expression and Behavioral Pharmacology in a Sexually Dimorphic Manner in Huntington’s Disease Transgenic Mice

Huntington’s disease (HD) is a neurodegenerative disorder caused by a tandem repeat mutation encoding an expanded polyglutamine tract in the huntingtin protein, which leads to cognitive, psychiatric and motor dysfunction. Exposure to environmental enrichment (EE), which enhances levels of cognitive...

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Detalles Bibliográficos
Autores principales: Zajac, Michelle S., Renoir, Thibault, Perreau, Victoria M., Li, Shanshan, Adams, Wendy, van den Buuse, Maarten, Hannan, Anthony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295568/
https://www.ncbi.nlm.nih.gov/pubmed/30618600
http://dx.doi.org/10.3389/fnmol.2018.00433