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Short-Term Environmental Stimulation Spatiotemporally Modulates Specific Serotonin Receptor Gene Expression and Behavioral Pharmacology in a Sexually Dimorphic Manner in Huntington’s Disease Transgenic Mice
Huntington’s disease (HD) is a neurodegenerative disorder caused by a tandem repeat mutation encoding an expanded polyglutamine tract in the huntingtin protein, which leads to cognitive, psychiatric and motor dysfunction. Exposure to environmental enrichment (EE), which enhances levels of cognitive...
Autores principales: | Zajac, Michelle S., Renoir, Thibault, Perreau, Victoria M., Li, Shanshan, Adams, Wendy, van den Buuse, Maarten, Hannan, Anthony J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295568/ https://www.ncbi.nlm.nih.gov/pubmed/30618600 http://dx.doi.org/10.3389/fnmol.2018.00433 |
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