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Engineered Streptomyces lividans Strains for Optimal Identification and Expression of Cryptic Biosynthetic Gene Clusters

Streptomyces lividans is a suitable host for the heterologous expression of biosynthetic gene clusters (BGCs) from actinomycetes to discover “cryptic” secondary metabolites. To improve the heterologous expression of BGCs, herein we optimized S. lividans strain SBT5 via the stepwise integration of th...

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Detalles Bibliográficos
Autores principales:	Peng, Qinying, Gao, Guixi, Lü, Jin, Long, Qingshan, Chen, Xuefei, Zhang, Fei, Xu, Min, Liu, Kai, Wang, Yemin, Deng, Zixin, Li, Zhiyong, Tao, Meifeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295570/ https://www.ncbi.nlm.nih.gov/pubmed/30619133 http://dx.doi.org/10.3389/fmicb.2018.03042

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