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Hepatocyte nuclear factor 4α regulates megalin expression in proximal tubular cells

Hepatocyte nuclear factor 4α (HNF4α) is a member of the nuclear receptor superfamily and upregulates expression of many genes in the liver, pancreas, small intestine, and colon. HNF4α is also highly expressed in proximal tubular epithelial cells (PTECs) in kidney. PTECs reabsorb various substances t...

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Detalles Bibliográficos
Autores principales: Sasaki, Shota, Hara, Ayami, Sakaguchi, Masakiyo, Nangaku, Masaomi, Inoue, Yusuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295598/
https://www.ncbi.nlm.nih.gov/pubmed/30582012
http://dx.doi.org/10.1016/j.bbrep.2018.11.010

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