Establishment of X-linked Alport syndrome model mice with a Col4a5 R471X mutation

Alport syndrome (AS) is an inherited disorder characterized by glomerular basement membrane (GBM) abnormality and development of chronic kidney disease at an early age. The cause of AS is a genetic mutation in type IV collagen, and more than 80% of patients have X-linked AS (XLAS) with mutation in C...

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Detalles Bibliográficos
Autores principales: Hashikami, Kentarou, Asahina, Makoto, Nozu, Kandai, Iijima, Kazumoto, Nagata, Michio, Takeyama, Michiyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295608/
https://www.ncbi.nlm.nih.gov/pubmed/30582011
http://dx.doi.org/10.1016/j.bbrep.2018.12.003

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