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Study of correlation between the NAT2 phenotype and genotype status among Greenlandic Inuit
N-acetyltransferase 2 (NAT2) is the main enzyme metabolizing isoniazid and genotype-based treatment has been studied for years without becoming common practice. To investigate whether genotype-based isoniazid treatment is feasible in Greenland, we sequenced the coding sequence of NAT2 and determined...
Autores principales: | Birch Kristensen, Emilie, Yakimov, Victor, Bjorn-Mortensen, Karen, Soborg, Bolette, Koch, Anders, Andersson, Mikael, Birch Kristensen, Kasper, Michelsen, Sascha Wilk, Skotte, Line, Ahrendt Bjerregaard, Anne, Blaszkewicz, Meinolf, Golka, Klaus, Hengstler, Jan G., Feenstra, Bjarke, Melbye, Mads, Geller, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Leibniz Research Centre for Working Environment and Human Factors
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295636/ https://www.ncbi.nlm.nih.gov/pubmed/30564082 http://dx.doi.org/10.17179/excli2018-1671 |
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