Everolimus, a mammalian target of rapamycin inhibitor, ameliorated streptozotocin-induced learning and memory deficits via neurochemical alterations in male rats

Everolimus (EVR), as a rapamycin analog, is a selective inhibitor of the mammalian target of rapamycin (mTOR) kinase and its associated signaling pathway. mTOR is a serine/threonine protein kinase and its hyperactivity is involved in the pathophysiology of Alzheimer's disease (AD) and associate...

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Detalles Bibliográficos
Autores principales: Fanoudi, Sahar, Hosseini, Mahmoud, Alavi, Mohaddeseh Sadat, Boroushaki, Mohammad Taher, Hosseini, Azar, Sadeghnia, Hamid R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295637/
https://www.ncbi.nlm.nih.gov/pubmed/30564080
http://dx.doi.org/10.17179/excli2018-1626

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