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Evaluation of microsatellite instability in tumor and tumor marginal samples of sporadic colorectal cancer using mononucleotide markers

Microsatellite instability (MSI) is a unique molecular alteration that is due to a defective DNA mismatch repair (MMR) system. Approximately, 15-20 % of sporadic colorectal cancers (CRC) display MSI. Determination of MSI status in CRC has prognostic and predictive implications. Additionally, detecti...

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Detalles Bibliográficos
Autores principales: Nouri Nojadeh, Jafar, Hashemzadeh, Shahriar, Samadi Kafil, Hossein, Behrouz Sharif, Shahin, Eftekharsadat, Amirtaher, Ghasemnejad, Tohid, Ghojazadeh, Mortaza, Sakhinia, Ebrahim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295640/
https://www.ncbi.nlm.nih.gov/pubmed/30564073
http://dx.doi.org/10.17179/excli2018-1455