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Processing Escape Mechanisms Through Altered Proteasomal Cleavage of Epitopes Affect Immune Response in Pulmonary Neuroendocrine Tumors

BACKGROUND: Immunotherapy, especially immune checkpoint inhibition, is one of the most sophisticated approaches in cancer therapy. Immune checkpoint inhibition has already been successfully applied for treatment of non-small cell lung cancer and various other entities. Unfortunately, 60% of the case...

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Detalles Bibliográficos
Autores principales: Wessolly, Michael, Walter, Robert F. H., Vollbrecht, Claudia, Werner, Robert, Borchert, Sabrina, Schmeller, Jan, Mairinger, Elena, Herold, Thomas, Streubel, Anna, Christoph, Daniel C., Eberhardt, Wilfried E. E., Kollmeier, Jens, Mairinger, Thomas, Schmid, Kurt W., Wohlschlaeger, Jeremias, Hager, Thomas, Mairinger, Fabian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295696/
http://dx.doi.org/10.1177/1533033818818418