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Management of sub-centimeter recurrent hepatocellular carcinoma after curative treatment: Current status and future

Hepatocellular carcinomas (HCCs) frequently recur despite initial successful surgical resection or local ablation therapy. Diagnostic methods for small HCCs have improved with the introduction of gadoxetic acid-enhanced liver magnetic resonance imaging and diffusion-weighted imaging (DWI). Currently...

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Autores principales: Lee, Min Woo, Lim, Hyo Keun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295838/
https://www.ncbi.nlm.nih.gov/pubmed/30581270
http://dx.doi.org/10.3748/wjg.v24.i46.5215
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author Lee, Min Woo
Lim, Hyo Keun
author_facet Lee, Min Woo
Lim, Hyo Keun
author_sort Lee, Min Woo
collection PubMed
description Hepatocellular carcinomas (HCCs) frequently recur despite initial successful surgical resection or local ablation therapy. Diagnostic methods for small HCCs have improved with the introduction of gadoxetic acid-enhanced liver magnetic resonance imaging and diffusion-weighted imaging (DWI). Currently, sub-centimeter recurrent nodules showing typical hallmark imaging findings of HCC are frequently detected in patients with a treatment history for HCC. With five typical magnetic resonance findings, including arterial enhancement, washout on portal or transitional phase, high signal intensity on both T2-weighted image and DWI, and low signal intensity on hepatobiliary phase, sub-centimeter recurrent HCC can be diagnosed with high accuracy. Although more information is needed to determine the treatment of choice, local ablation therapy under fusion imaging and/or contrast-enhanced ultrasound guidance or cone-beam computed tomography-guided chemoembolization seem to be promising as they are effective and safe for the management of sub-centimeter recurrent HCCs.
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spelling pubmed-62958382018-12-21 Management of sub-centimeter recurrent hepatocellular carcinoma after curative treatment: Current status and future Lee, Min Woo Lim, Hyo Keun World J Gastroenterol Minireviews Hepatocellular carcinomas (HCCs) frequently recur despite initial successful surgical resection or local ablation therapy. Diagnostic methods for small HCCs have improved with the introduction of gadoxetic acid-enhanced liver magnetic resonance imaging and diffusion-weighted imaging (DWI). Currently, sub-centimeter recurrent nodules showing typical hallmark imaging findings of HCC are frequently detected in patients with a treatment history for HCC. With five typical magnetic resonance findings, including arterial enhancement, washout on portal or transitional phase, high signal intensity on both T2-weighted image and DWI, and low signal intensity on hepatobiliary phase, sub-centimeter recurrent HCC can be diagnosed with high accuracy. Although more information is needed to determine the treatment of choice, local ablation therapy under fusion imaging and/or contrast-enhanced ultrasound guidance or cone-beam computed tomography-guided chemoembolization seem to be promising as they are effective and safe for the management of sub-centimeter recurrent HCCs. Baishideng Publishing Group Inc 2018-12-14 2018-12-14 /pmc/articles/PMC6295838/ /pubmed/30581270 http://dx.doi.org/10.3748/wjg.v24.i46.5215 Text en ©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Minireviews
Lee, Min Woo
Lim, Hyo Keun
Management of sub-centimeter recurrent hepatocellular carcinoma after curative treatment: Current status and future
title Management of sub-centimeter recurrent hepatocellular carcinoma after curative treatment: Current status and future
title_full Management of sub-centimeter recurrent hepatocellular carcinoma after curative treatment: Current status and future
title_fullStr Management of sub-centimeter recurrent hepatocellular carcinoma after curative treatment: Current status and future
title_full_unstemmed Management of sub-centimeter recurrent hepatocellular carcinoma after curative treatment: Current status and future
title_short Management of sub-centimeter recurrent hepatocellular carcinoma after curative treatment: Current status and future
title_sort management of sub-centimeter recurrent hepatocellular carcinoma after curative treatment: current status and future
topic Minireviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295838/
https://www.ncbi.nlm.nih.gov/pubmed/30581270
http://dx.doi.org/10.3748/wjg.v24.i46.5215
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