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Management of sub-centimeter recurrent hepatocellular carcinoma after curative treatment: Current status and future
Hepatocellular carcinomas (HCCs) frequently recur despite initial successful surgical resection or local ablation therapy. Diagnostic methods for small HCCs have improved with the introduction of gadoxetic acid-enhanced liver magnetic resonance imaging and diffusion-weighted imaging (DWI). Currently...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295838/ https://www.ncbi.nlm.nih.gov/pubmed/30581270 http://dx.doi.org/10.3748/wjg.v24.i46.5215 |
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author | Lee, Min Woo Lim, Hyo Keun |
author_facet | Lee, Min Woo Lim, Hyo Keun |
author_sort | Lee, Min Woo |
collection | PubMed |
description | Hepatocellular carcinomas (HCCs) frequently recur despite initial successful surgical resection or local ablation therapy. Diagnostic methods for small HCCs have improved with the introduction of gadoxetic acid-enhanced liver magnetic resonance imaging and diffusion-weighted imaging (DWI). Currently, sub-centimeter recurrent nodules showing typical hallmark imaging findings of HCC are frequently detected in patients with a treatment history for HCC. With five typical magnetic resonance findings, including arterial enhancement, washout on portal or transitional phase, high signal intensity on both T2-weighted image and DWI, and low signal intensity on hepatobiliary phase, sub-centimeter recurrent HCC can be diagnosed with high accuracy. Although more information is needed to determine the treatment of choice, local ablation therapy under fusion imaging and/or contrast-enhanced ultrasound guidance or cone-beam computed tomography-guided chemoembolization seem to be promising as they are effective and safe for the management of sub-centimeter recurrent HCCs. |
format | Online Article Text |
id | pubmed-6295838 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Baishideng Publishing Group Inc |
record_format | MEDLINE/PubMed |
spelling | pubmed-62958382018-12-21 Management of sub-centimeter recurrent hepatocellular carcinoma after curative treatment: Current status and future Lee, Min Woo Lim, Hyo Keun World J Gastroenterol Minireviews Hepatocellular carcinomas (HCCs) frequently recur despite initial successful surgical resection or local ablation therapy. Diagnostic methods for small HCCs have improved with the introduction of gadoxetic acid-enhanced liver magnetic resonance imaging and diffusion-weighted imaging (DWI). Currently, sub-centimeter recurrent nodules showing typical hallmark imaging findings of HCC are frequently detected in patients with a treatment history for HCC. With five typical magnetic resonance findings, including arterial enhancement, washout on portal or transitional phase, high signal intensity on both T2-weighted image and DWI, and low signal intensity on hepatobiliary phase, sub-centimeter recurrent HCC can be diagnosed with high accuracy. Although more information is needed to determine the treatment of choice, local ablation therapy under fusion imaging and/or contrast-enhanced ultrasound guidance or cone-beam computed tomography-guided chemoembolization seem to be promising as they are effective and safe for the management of sub-centimeter recurrent HCCs. Baishideng Publishing Group Inc 2018-12-14 2018-12-14 /pmc/articles/PMC6295838/ /pubmed/30581270 http://dx.doi.org/10.3748/wjg.v24.i46.5215 Text en ©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. |
spellingShingle | Minireviews Lee, Min Woo Lim, Hyo Keun Management of sub-centimeter recurrent hepatocellular carcinoma after curative treatment: Current status and future |
title | Management of sub-centimeter recurrent hepatocellular carcinoma after curative treatment: Current status and future |
title_full | Management of sub-centimeter recurrent hepatocellular carcinoma after curative treatment: Current status and future |
title_fullStr | Management of sub-centimeter recurrent hepatocellular carcinoma after curative treatment: Current status and future |
title_full_unstemmed | Management of sub-centimeter recurrent hepatocellular carcinoma after curative treatment: Current status and future |
title_short | Management of sub-centimeter recurrent hepatocellular carcinoma after curative treatment: Current status and future |
title_sort | management of sub-centimeter recurrent hepatocellular carcinoma after curative treatment: current status and future |
topic | Minireviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295838/ https://www.ncbi.nlm.nih.gov/pubmed/30581270 http://dx.doi.org/10.3748/wjg.v24.i46.5215 |
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