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The influence of GAPT extraction on synapse loss of APPswe/PS1dE9 transgenic mice via adjusting Bcl-2/Bax balance

INTRODUCTION: The degeneration of memory-focused synapses play important roles in Alzheimer's disease (AD) pathogenesis, while it is not well known how β amyloid interferes neuron apoptosis and how a herbal combination GAPT influence synapse loss and neuronal apoptosis pathways of APP/PS1 trans...

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Detalles Bibliográficos
Autores principales:	Shi, Jing, Zhang, Xuekai, Ni, Jingnian, Wei, Mingqing, Li, Ting, Zhou, Bingling, Liu, Xiawei, Zhang, Liping, Wang, Pengwen, Tian, Jinzhou, Wang, Yongyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Featured Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295930/ https://www.ncbi.nlm.nih.gov/pubmed/30581978 http://dx.doi.org/10.1016/j.trci.2018.10.008

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