Cargando…

Inflammation-mediated muscle metabolic dysregulation local and remote to the site of major abdominal surgery

BACKGROUND & AIMS: Postoperative hyperglycaemia is common in patients having major surgery and is associated with adverse outcomes. This study aimed to determine whether bacteraemia contributed to postoperative systemic inflammation, and whether increases in the expression of muscle mRNAs and pr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Varadhan, Krishna K., Constantin-Teodosiu, Dumitru, Constantin, Despina, Greenhaff, Paul L., Lobo, Dileep N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295976/ https://www.ncbi.nlm.nih.gov/pubmed/29129636 http://dx.doi.org/10.1016/j.clnu.2017.10.020

Ejemplares similares

Major elective abdominal surgery acutely impairs lower limb muscle pyruvate dehydrogenase complex activity and mitochondrial function
por: Atkins, Ryan, et al.
Publicado: (2021)

The Regulatory Roles of PPARs in Skeletal Muscle Fuel Metabolism and Inflammation: Impact of PPAR Agonism on Muscle in Chronic Disease, Contraction and Sepsis
por: Crossland, Hannah, et al.
Publicado: (2021)

Molecular Mechanisms of Muscle Fatigue
por: Constantin-Teodosiu, Dumitru, et al.
Publicado: (2021)

Skeletal muscle dysregulation in rheumatoid arthritis: Metabolic and molecular markers in a rodent model and patients
por: Casanova-Vallve, Nuria, et al.
Publicado: (2020)

PPARα, δ and FOXO1 Gene Silencing Overturns Palmitate-Induced Inhibition of Pyruvate Oxidation Differentially in C2C12 Myotubes
por: Chien, Hung-Che, et al.
Publicado: (2021)

The Role of FOXO and PPAR Transcription Factors in Diet-Mediated Inhibition of PDC Activation and Carbohydrate Oxidation During Exercise in Humans and the Role of Pharmacological Activation of PDC in Overriding These Changes
por: Constantin-Teodosiu, Dumitru, et al.
Publicado: (2012)

The impact of immobilisation and inflammation on the regulation of muscle mass and insulin resistance: different routes to similar end‐points
por: Crossland, Hannah, et al.
Publicado: (2018)

PPARδ and FOXO1 Mediate Palmitate-Induced Inhibition of Muscle Pyruvate Dehydrogenase Complex and CHO Oxidation, Events Reversed by Electrical Pulse Stimulation
por: Chien, Hung-Che, et al.
Publicado: (2020)

Whole-body and muscle responses to aerobic exercise training and withdrawal in ageing and COPD
por: Latimer, Lorna E., et al.
Publicado: (2022)

LTE: Does caffeine truly raise muscle carnitine in humans?
por: Constantin‐Teodosiu, Dumitru
Publicado: (2023)

Regulation of Muscle Pyruvate Dehydrogenase Complex in Insulin Resistance: Effects of Exercise and Dichloroacetate
por: Constantin-Teodosiu, Dumitru
Publicado: (2013)

Increasing cardiac pyruvate dehydrogenase flux during chronic hypoxia improves acute hypoxic tolerance
por: Handzlik, Michal K., et al.
Publicado: (2018)

Effects of Endotoxaemia on Protein Metabolism in Rat Fast-Twitch Skeletal Muscle and Myocardium
por: Murton, Andrew J., et al.
Publicado: (2009)

Human adaptation to immobilization: Novel insights of impacts on glucose disposal and fuel utilization
por: Shur, Natalie F., et al.
Publicado: (2022)

Statin myalgia is not associated with reduced muscle strength, mass or protein turnover in older male volunteers, but is allied with a slowing of time to peak power output, insulin resistance and differential muscle mRNA expression
por: Mallinson, Joanne E., et al.
Publicado: (2015)

Does carnitine supplementation truly increase whole‐body fat oxidation in older male adults during moderate‐intensity exercise?
por: Constantin‐Teodosiu, Dumitru
Publicado: (2021)

Potential role for pyruvate kinase M2 in the regulation of murine cardiac glycolytic flux during in vivo chronic hypoxia
por: Handzlik, Michal K., et al.
Publicado: (2021)

Degenerin channel activation causes caspase‐mediated protein degradation and mitochondrial dysfunction in adult C. elegans muscle
por: Gaffney, Christopher J., et al.
Publicado: (2015)

Greater loss of mitochondrial function with ageing is associated with earlier onset of sarcopenia in C. elegans
por: Gaffney, Christopher J., et al.
Publicado: (2018)

Immunohistochemical expression of mitochondrial membrane complexes (MMCs) I, III, IV and V in malignant and benign periampullary epithelium: a potential target for drug therapy of periampullary cancer?
por: Aloysius, Mark M, et al.
Publicado: (2010)

The integrin-adhesome is required to maintain muscle structure, mitochondrial ATP production, and movement forces in Caenorhabditis elegans
por: Etheridge, Timothy, et al.
Publicado: (2015)

The effects of elective abdominal surgery on protein turnover: A meta-analysis of stable isotope techniques to investigate postoperative catabolism
por: Jaconelli, Matthew, et al.
Publicado: (2022)

Safety and efficacy of antibiotics compared with appendicectomy for treatment of uncomplicated acute appendicitis: meta-analysis of randomised controlled trials
por: Varadhan, Krishna K, et al.
Publicado: (2012)

Spinal neuronal excitability and neuroinflammation in a model of chemotherapeutic neuropathic pain: targeting the resolution pathways
por: Meesawatsom, Pongsatorn, et al.
Publicado: (2020)

Do Antiretroviral Drugs Protect From Multiple Sclerosis by Inhibiting Expression of MS-Associated Retrovirus?
por: Morandi, Elena, et al.
Publicado: (2019)

Impact of transcutaneous neuromuscular electrical stimulation or resistance exercise on skeletal muscle mRNA expression in COPD
por: Latimer, Lorna E, et al.
Publicado: (2019)

Intraoperative Goal-directed Fluid Therapy in Elective Major Abdominal Surgery: A Meta-analysis of Randomized Controlled Trials
por: Rollins, Katie E., et al.
Publicado: (2016)

Inflammation: A key process in skin tumorigenesis
por: Neagu, Monica, et al.
Publicado: (2019)

Dysregulations of Key Regulators of Angiogenesis and Inflammation in Abdominal Aortic Aneurysm
por: Zalewski, Daniel, et al.
Publicado: (2023)

In vitro Exposure to Inflammatory Mediators Affects the Differentiation of Mesenchymal Progenitors
por: Marsh, S., et al.
Publicado: (2022)

Abdominal Wall Endometriosis: Two Case Reports and Literature Review
por: Doroftei, Bogdan, et al.
Publicado: (2020)

Pre-Operative nutrition In Neck of femur Trial (POINT) - carbohydrate loading in patients with fragility hip fracture: study protocol for a randomised controlled trial
por: Moppett, Iain K, et al.
Publicado: (2014)

Testosterone therapy induces molecular programming augmenting physiological adaptations to resistance exercise in older men
por: Gharahdaghi, Nima, et al.
Publicado: (2019)

Differential pain response at local and remote muscle sites following aerobic cycling exercise at mild and moderate intensity
por: Micalos, Peter S., et al.
Publicado: (2016)

Resistance to Aerobic Exercise Training Causes Metabolic Dysfunction and Reveals Novel Exercise-Regulated Signaling Networks
por: Lessard, Sarah J., et al.
Publicado: (2013)

Inorganic nitrate and nitrite supplementation fails to improve skeletal muscle mitochondrial efficiency in mice and humans
por: Ntessalen, Maria, et al.
Publicado: (2020)

Exercises in functional analysis
por: Costara, Constantin, et al.
Publicado: (2003)

Age-Associated Dysregulation of Integrin Function in Vascular Smooth Muscle
por: Ojha, Krishna Raj, et al.
Publicado: (2022)

Myocardial infarction causes inflammation and leukocyte recruitment at remote sites in the myocardium and in the renal glomerulus
por: Ruparelia, Neil, et al.
Publicado: (2013)

Plant Bioactives in the Treatment of Inflammation of Skeletal Muscles: A Molecular Perspective
por: Karati, Dipanjan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_nqa1bhiakvnaotncbd11orc2c7