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Palmitate- and C6 ceramide-induced Tnnt3 pre-mRNA alternative splicing occurs in a PP2A dependent manner

BACKGROUND: In a previous study, we showed that consumption of diets enriched in saturated fatty acids causes changes in alternative splicing of pre-mRNAs encoding a number of proteins in rat skeletal muscle, including the one encoding skeletal muscle Troponin T (Tnnt3). However, whether saturated f...

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Detalles Bibliográficos
Autores principales: Black, Adam J., Schilder, Rudolf J., Kimball, Scot R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296074/
https://www.ncbi.nlm.nih.gov/pubmed/30564278
http://dx.doi.org/10.1186/s12986-018-0326-3

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