BRAF V600E mutation and 9p21: CDKN2A/B and MTAP co-deletions - Markers in the clinical stratification of pediatric gliomas

BACKGROUND: Genetic alterations in pediatric primary brain tumors can be used as diagnostic and prognostic markers and are the basis for the development of new target therapies that, ideally, would be associated with lower mortality and morbidity. This study evaluates the incidence and interplay of...

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Detalles Bibliográficos
Autores principales: Frazão, Laura, do Carmo Martins, Maria, Nunes, Vasco Moura, Pimentel, José, Faria, Claudia, Miguéns, José, Sagarribay, Amets, Matos, Mário, Salgado, Duarte, Nunes, Sofia, Mafra, Manuela, Roque, Lúcia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296141/
https://www.ncbi.nlm.nih.gov/pubmed/30558563
http://dx.doi.org/10.1186/s12885-018-5120-0

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