Alzheimer's disease in Down syndrome: An overlooked population for prevention trials

The discovery that adults with Down syndrome (DS) have neuropathological features identical to individuals with sporadic Alzheimer's disease (AD) played a key role in the identification of the amyloid precursor protein gene on chromosome 21 and resulted in the amyloid cascade hypothesis. Indivi...

Descripción completa

Detalles Bibliográficos
Autores principales: Strydom, André, Coppus, Antonia, Blesa, Rafael, Danek, Adrian, Fortea, Juan, Hardy, John, Levin, Johannes, Nuebling, Georg, Rebillat, Anne-Sophie, Ritchie, Craig, van Duijn, Cornelia, Zaman, Shahid, Zetterberg, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296162/
https://www.ncbi.nlm.nih.gov/pubmed/30581976
http://dx.doi.org/10.1016/j.trci.2018.10.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296162/
https://www.ncbi.nlm.nih.gov/pubmed/30581976
http://dx.doi.org/10.1016/j.trci.2018.10.006

Ejemplares similares