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Alzheimer's disease in Down syndrome: An overlooked population for prevention trials
The discovery that adults with Down syndrome (DS) have neuropathological features identical to individuals with sporadic Alzheimer's disease (AD) played a key role in the identification of the amyloid precursor protein gene on chromosome 21 and resulted in the amyloid cascade hypothesis. Indivi...
Autores principales: | Strydom, André, Coppus, Antonia, Blesa, Rafael, Danek, Adrian, Fortea, Juan, Hardy, John, Levin, Johannes, Nuebling, Georg, Rebillat, Anne-Sophie, Ritchie, Craig, van Duijn, Cornelia, Zaman, Shahid, Zetterberg, Henrik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296162/ https://www.ncbi.nlm.nih.gov/pubmed/30581976 http://dx.doi.org/10.1016/j.trci.2018.10.006 |
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