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Oxidative stress‐induced structural changes in the microtubule‐associated flavoenzyme Irc15p from Saccharomyces cerevisiae

The genome of the yeast Saccharomyces cerevisiae encodes a canonical lipoamide dehydrogenase (Lpd1p) as part of the pyruvate dehydrogenase complex and a highly similar protein termed Irc15p (increased recombination centers 15). In contrast to Lpd1p, Irc15p lacks a pair of redox active cysteine resid...

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Detalles Bibliográficos
Autores principales: Koch, Karin, Strandback, Emilia, Jha, Shalinee, Richter, Gesa, Bourgeois, Benjamin, Madl, Tobias, Macheroux, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296175/
https://www.ncbi.nlm.nih.gov/pubmed/30267443
http://dx.doi.org/10.1002/pro.3517