Silver-mediated oxidative functionalization of alkylsilanes

A general approach to the functionalization of aliphatic C–Si bonds in the presence of silver salts and oxidants has been reported. This strategy encompasses a range of valuable C–Si transformations, including the direct conversions of a C–Si bond to C–OCF(3), C–OBz, C–OCOCF(3), C–SCF(3), C–SCN, and...

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Detalles Bibliográficos
Autores principales: Wang, Feng, Xu, Peng, Cong, Fei, Tang, Pingping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296296/
https://www.ncbi.nlm.nih.gov/pubmed/30627401
http://dx.doi.org/10.1039/c8sc03730b
Descripción
Sumario:A general approach to the functionalization of aliphatic C–Si bonds in the presence of silver salts and oxidants has been reported. This strategy encompasses a range of valuable C–Si transformations, including the direct conversions of a C–Si bond to C–OCF(3), C–OBz, C–OCOCF(3), C–SCF(3), C–SCN, and C–N(3) bonds. Among them, trifluoromethoxylation of alkylsilanes is reported for the first time. In addition, mechanistic studies indicate that this reaction may proceed through a radical mechanism.

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