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Copper-mediated 1,2-bis(trifluoromethylation) of arynes
We herein describe an unprecedented 1,2-bis(trifluoromethylation) of arynes with [CuCF(3)] in the presence of an oxidant DDQ. The method allows the rapid construction of a new class of 1,2-bis(trifluoromethyl)arenes in one-step from aryne precursors under mild conditions. Its synthetic utility has b...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296300/ https://www.ncbi.nlm.nih.gov/pubmed/30627405 http://dx.doi.org/10.1039/c8sc03754j |