LILRB4 signaling in leukemia cells mediates T cell suppression and tumor infiltration

Immune checkpoint blockade therapy has been successful in treating some types of cancers but has not shown clinical benefits for treating leukemia (1). This result suggests that leukemia exploits unique escape mechanisms. Certain immune inhibitory receptors that are expressed by normal immune cells...

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Detalles Bibliográficos
Autores principales: Deng, Mi, Gui, Xun, Kim, Jaehyup, Xie, Li, Chen, Weina, Li, Zunling, He, Licai, Chen, Yuanzhi, Chen, Heyu, Luo, Weiguang, Lu, Zhigang, Xie, Jingjing, Churchill, Hywyn, Xu, Yixiang, Zhou, Zhan, Wu, Guojin, Yu, Chenyi, John, Samuel, Hirayasu, Kouyuki, Nguyen, Nam, Liu, Xiaoye, Huang, Fangfang, Li, Leike, Deng, Hui, Tang, Haidong, Sadek, Ali H., Zhang, Lingbo, Huang, Tao, Zou, Yizhou, Chen, Benjamin, Zhu, Hong, Arase, Hisashi, Xia, Ningshao, Jiang, Youxing, Collins, Robert, You, M. James, Homsi, Jade, Unni, Nisha, Lewis, Cheryl, Chen, Guo-Qiang, Fu, Yang-Xin, Liao, X. Charlene, An, Zhiqiang, Zheng, Junke, Zhang, Ningyan, Zhang, Cheng Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296374/
https://www.ncbi.nlm.nih.gov/pubmed/30333625
http://dx.doi.org/10.1038/s41586-018-0615-z

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