Biosynthesis of silver nanoparticles formation from Caesalpinia pulcherrima stem metabolites and their broad spectrum biological activities

The present work illustrates eco-friendly, rapid and cost effective method of AgNPs synthesis using C. pulcherrima stem extract. Initially, various physico chemical factors were optimized. Characterization was done by different spectroscopic and microscopic analysis. AgNPs were spherical in shape wi...

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Detalles Bibliográficos
Autores principales: Moteriya, Pooja, Chanda, Sumitra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academy of Scientific Research and Technology, Egypt 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296618/
https://www.ncbi.nlm.nih.gov/pubmed/30647712
http://dx.doi.org/10.1016/j.jgeb.2017.12.003
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author Moteriya, Pooja
Chanda, Sumitra
author_facet Moteriya, Pooja
Chanda, Sumitra
author_sort Moteriya, Pooja
collection PubMed
description The present work illustrates eco-friendly, rapid and cost effective method of AgNPs synthesis using C. pulcherrima stem extract. Initially, various physico chemical factors were optimized. Characterization was done by different spectroscopic and microscopic analysis. AgNPs were spherical in shape with an average size of 8 nm. AgNPs showed good synergistic antimicrobial, antibiofilm and antioxidant activity. The cytotoxicity effect against HeLa cancer cell line was dose dependent while genotoxic study revealed the non toxic nature of AgNPs at lower concentration. The results suggest that AgNPs from C. pulcherrima stem extract have great potential in biomedical applications.
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spelling pubmed-62966182019-01-15 Biosynthesis of silver nanoparticles formation from Caesalpinia pulcherrima stem metabolites and their broad spectrum biological activities Moteriya, Pooja Chanda, Sumitra J Genet Eng Biotechnol Original Article The present work illustrates eco-friendly, rapid and cost effective method of AgNPs synthesis using C. pulcherrima stem extract. Initially, various physico chemical factors were optimized. Characterization was done by different spectroscopic and microscopic analysis. AgNPs were spherical in shape with an average size of 8 nm. AgNPs showed good synergistic antimicrobial, antibiofilm and antioxidant activity. The cytotoxicity effect against HeLa cancer cell line was dose dependent while genotoxic study revealed the non toxic nature of AgNPs at lower concentration. The results suggest that AgNPs from C. pulcherrima stem extract have great potential in biomedical applications. Academy of Scientific Research and Technology, Egypt 2018-06 2018-01-04 /pmc/articles/PMC6296618/ /pubmed/30647712 http://dx.doi.org/10.1016/j.jgeb.2017.12.003 Text en © 2018 Production and hosting by Elsevier B.V. on behalf of Academy of Scientific Research & Technology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Moteriya, Pooja
Chanda, Sumitra
Biosynthesis of silver nanoparticles formation from Caesalpinia pulcherrima stem metabolites and their broad spectrum biological activities
title Biosynthesis of silver nanoparticles formation from Caesalpinia pulcherrima stem metabolites and their broad spectrum biological activities
title_full Biosynthesis of silver nanoparticles formation from Caesalpinia pulcherrima stem metabolites and their broad spectrum biological activities
title_fullStr Biosynthesis of silver nanoparticles formation from Caesalpinia pulcherrima stem metabolites and their broad spectrum biological activities
title_full_unstemmed Biosynthesis of silver nanoparticles formation from Caesalpinia pulcherrima stem metabolites and their broad spectrum biological activities
title_short Biosynthesis of silver nanoparticles formation from Caesalpinia pulcherrima stem metabolites and their broad spectrum biological activities
title_sort biosynthesis of silver nanoparticles formation from caesalpinia pulcherrima stem metabolites and their broad spectrum biological activities
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296618/
https://www.ncbi.nlm.nih.gov/pubmed/30647712
http://dx.doi.org/10.1016/j.jgeb.2017.12.003
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