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Insights on the impact of mitochondrial organisation on bioenergetics in high-resolution computational models of cardiac cell architecture
Recent electron microscopy data have revealed that cardiac mitochondria are not arranged in crystalline columns but are organised with several mitochondria aggregated into columns of varying sizes spanning the cell cross-section. This raises the question—how does the mitochondrial arrangement affect...
Autores principales: | Ghosh, Shouryadipta, Tran, Kenneth, Delbridge, Lea M. D., Hickey, Anthony J. R., Hanssen, Eric, Crampin, Edmund J., Rajagopal, Vijay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296675/ https://www.ncbi.nlm.nih.gov/pubmed/30517098 http://dx.doi.org/10.1371/journal.pcbi.1006640 |
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