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Empirically developed dietary inflammatory potential (EDIP) in patients candidate for coronary artery bypass grafting surgery (CABG): Association with metabolic parameters, dietary antioxidant quality score and dietary phytochemical index
AIMS: It has been suggested that empirically developed dietary inflammatory potential (EDIP) is a diagnostic tool for assessment of inflammatory potential of diet in prediction of risk factors related to chronic disease. In the current work, we examined the association between EDIP with cardio-metab...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296711/ https://www.ncbi.nlm.nih.gov/pubmed/30557399 http://dx.doi.org/10.1371/journal.pone.0208711 |
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author | Abbasalizad Farhangi, Mahdieh Najafi, Mahdi |
author_facet | Abbasalizad Farhangi, Mahdieh Najafi, Mahdi |
author_sort | Abbasalizad Farhangi, Mahdieh |
collection | PubMed |
description | AIMS: It has been suggested that empirically developed dietary inflammatory potential (EDIP) is a diagnostic tool for assessment of inflammatory potential of diet in prediction of risk factors related to chronic disease. In the current work, we examined the association between EDIP with cardio-metabolic risk factors, dietary antioxidant quality score (DAQs), dietary phytochemical index (DPI) and Mediterranean dietary quality index (MEDQI) in patients candidate for CABG. MATERIALS AND METHODS: In the current cross-sectional study, the data obtained from Tehran- Heart Center-Coronary Outcome Measurement (THC-COM) study from 454 patients candidate for the CABG were used. Laboratory measurements including hemoglobin (Hb)-A1C, serum lipids, creatinine, blood urea nitrogen (BUN), hematocrit, Lp(a), telomerase activity, serum vitamin D and c-reactive protein (CRP) were measured with commercial laboratory methods. Dietary indices were measured according to the data obtained from with semi-quantitative FFQ. RESULTS: In the current work, patients in top quintile of EDIP had higher BMI and higher prevalence of hyperlipidemia compared with patients in lowest quintile (BMI: 28.08 ±3.68 vs 26.69 ± 3.67 and hyperlipidemia: 77.8 vs 65.5%; P < 0.05). Moreover, lower EDIP scores were accompanied with higher vitamin E (0.48 vs 0.4) and total dietary antioxidant scores (4.40 VS 4.28), higher dietary phytochemical scores (69.79 vs 58.29) and lower dietary Mediterranean quality scores (P < 0.05 and P < 0.01 respectively). In male patients, being at highest quintiles of EDIP make patients 2–5% more likely to have higher concentrations of serum cholesterol, BUN and Lp (a), and 6 to 8 times more likely to have higher creatinine and 66% more likely to have lower albumin concentrations compared with male patients in lowest quintiles. In female patients, lower HCT, higher creatinine, higher CRP concentrations and higher telomerase activity were also achieved by higher EDIP scores (P < 0.05). CONCLUSION: According to our finding, EDIP was associated with obesity, high prevalence of dyslipidemia and cardio-metabolic risk factors. Moreover, EDIP was in an inverse association with dietary antioxidant quality score and dietary phytochemical index. Therefore, EDIP could be assumed as a precise tool for estimating the CVD related risk factors among patients candidate for CABG. |
format | Online Article Text |
id | pubmed-6296711 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-62967112018-12-28 Empirically developed dietary inflammatory potential (EDIP) in patients candidate for coronary artery bypass grafting surgery (CABG): Association with metabolic parameters, dietary antioxidant quality score and dietary phytochemical index Abbasalizad Farhangi, Mahdieh Najafi, Mahdi PLoS One Research Article AIMS: It has been suggested that empirically developed dietary inflammatory potential (EDIP) is a diagnostic tool for assessment of inflammatory potential of diet in prediction of risk factors related to chronic disease. In the current work, we examined the association between EDIP with cardio-metabolic risk factors, dietary antioxidant quality score (DAQs), dietary phytochemical index (DPI) and Mediterranean dietary quality index (MEDQI) in patients candidate for CABG. MATERIALS AND METHODS: In the current cross-sectional study, the data obtained from Tehran- Heart Center-Coronary Outcome Measurement (THC-COM) study from 454 patients candidate for the CABG were used. Laboratory measurements including hemoglobin (Hb)-A1C, serum lipids, creatinine, blood urea nitrogen (BUN), hematocrit, Lp(a), telomerase activity, serum vitamin D and c-reactive protein (CRP) were measured with commercial laboratory methods. Dietary indices were measured according to the data obtained from with semi-quantitative FFQ. RESULTS: In the current work, patients in top quintile of EDIP had higher BMI and higher prevalence of hyperlipidemia compared with patients in lowest quintile (BMI: 28.08 ±3.68 vs 26.69 ± 3.67 and hyperlipidemia: 77.8 vs 65.5%; P < 0.05). Moreover, lower EDIP scores were accompanied with higher vitamin E (0.48 vs 0.4) and total dietary antioxidant scores (4.40 VS 4.28), higher dietary phytochemical scores (69.79 vs 58.29) and lower dietary Mediterranean quality scores (P < 0.05 and P < 0.01 respectively). In male patients, being at highest quintiles of EDIP make patients 2–5% more likely to have higher concentrations of serum cholesterol, BUN and Lp (a), and 6 to 8 times more likely to have higher creatinine and 66% more likely to have lower albumin concentrations compared with male patients in lowest quintiles. In female patients, lower HCT, higher creatinine, higher CRP concentrations and higher telomerase activity were also achieved by higher EDIP scores (P < 0.05). CONCLUSION: According to our finding, EDIP was associated with obesity, high prevalence of dyslipidemia and cardio-metabolic risk factors. Moreover, EDIP was in an inverse association with dietary antioxidant quality score and dietary phytochemical index. Therefore, EDIP could be assumed as a precise tool for estimating the CVD related risk factors among patients candidate for CABG. Public Library of Science 2018-12-17 /pmc/articles/PMC6296711/ /pubmed/30557399 http://dx.doi.org/10.1371/journal.pone.0208711 Text en © 2018 Abbasalizad Farhangi, Najafi http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Abbasalizad Farhangi, Mahdieh Najafi, Mahdi Empirically developed dietary inflammatory potential (EDIP) in patients candidate for coronary artery bypass grafting surgery (CABG): Association with metabolic parameters, dietary antioxidant quality score and dietary phytochemical index |
title | Empirically developed dietary inflammatory potential (EDIP) in patients candidate for coronary artery bypass grafting surgery (CABG): Association with metabolic parameters, dietary antioxidant quality score and dietary phytochemical index |
title_full | Empirically developed dietary inflammatory potential (EDIP) in patients candidate for coronary artery bypass grafting surgery (CABG): Association with metabolic parameters, dietary antioxidant quality score and dietary phytochemical index |
title_fullStr | Empirically developed dietary inflammatory potential (EDIP) in patients candidate for coronary artery bypass grafting surgery (CABG): Association with metabolic parameters, dietary antioxidant quality score and dietary phytochemical index |
title_full_unstemmed | Empirically developed dietary inflammatory potential (EDIP) in patients candidate for coronary artery bypass grafting surgery (CABG): Association with metabolic parameters, dietary antioxidant quality score and dietary phytochemical index |
title_short | Empirically developed dietary inflammatory potential (EDIP) in patients candidate for coronary artery bypass grafting surgery (CABG): Association with metabolic parameters, dietary antioxidant quality score and dietary phytochemical index |
title_sort | empirically developed dietary inflammatory potential (edip) in patients candidate for coronary artery bypass grafting surgery (cabg): association with metabolic parameters, dietary antioxidant quality score and dietary phytochemical index |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296711/ https://www.ncbi.nlm.nih.gov/pubmed/30557399 http://dx.doi.org/10.1371/journal.pone.0208711 |
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