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Empirically developed dietary inflammatory potential (EDIP) in patients candidate for coronary artery bypass grafting surgery (CABG): Association with metabolic parameters, dietary antioxidant quality score and dietary phytochemical index

AIMS: It has been suggested that empirically developed dietary inflammatory potential (EDIP) is a diagnostic tool for assessment of inflammatory potential of diet in prediction of risk factors related to chronic disease. In the current work, we examined the association between EDIP with cardio-metab...

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Autores principales: Abbasalizad Farhangi, Mahdieh, Najafi, Mahdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296711/
https://www.ncbi.nlm.nih.gov/pubmed/30557399
http://dx.doi.org/10.1371/journal.pone.0208711
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author Abbasalizad Farhangi, Mahdieh
Najafi, Mahdi
author_facet Abbasalizad Farhangi, Mahdieh
Najafi, Mahdi
author_sort Abbasalizad Farhangi, Mahdieh
collection PubMed
description AIMS: It has been suggested that empirically developed dietary inflammatory potential (EDIP) is a diagnostic tool for assessment of inflammatory potential of diet in prediction of risk factors related to chronic disease. In the current work, we examined the association between EDIP with cardio-metabolic risk factors, dietary antioxidant quality score (DAQs), dietary phytochemical index (DPI) and Mediterranean dietary quality index (MEDQI) in patients candidate for CABG. MATERIALS AND METHODS: In the current cross-sectional study, the data obtained from Tehran- Heart Center-Coronary Outcome Measurement (THC-COM) study from 454 patients candidate for the CABG were used. Laboratory measurements including hemoglobin (Hb)-A1C, serum lipids, creatinine, blood urea nitrogen (BUN), hematocrit, Lp(a), telomerase activity, serum vitamin D and c-reactive protein (CRP) were measured with commercial laboratory methods. Dietary indices were measured according to the data obtained from with semi-quantitative FFQ. RESULTS: In the current work, patients in top quintile of EDIP had higher BMI and higher prevalence of hyperlipidemia compared with patients in lowest quintile (BMI: 28.08 ±3.68 vs 26.69 ± 3.67 and hyperlipidemia: 77.8 vs 65.5%; P < 0.05). Moreover, lower EDIP scores were accompanied with higher vitamin E (0.48 vs 0.4) and total dietary antioxidant scores (4.40 VS 4.28), higher dietary phytochemical scores (69.79 vs 58.29) and lower dietary Mediterranean quality scores (P < 0.05 and P < 0.01 respectively). In male patients, being at highest quintiles of EDIP make patients 2–5% more likely to have higher concentrations of serum cholesterol, BUN and Lp (a), and 6 to 8 times more likely to have higher creatinine and 66% more likely to have lower albumin concentrations compared with male patients in lowest quintiles. In female patients, lower HCT, higher creatinine, higher CRP concentrations and higher telomerase activity were also achieved by higher EDIP scores (P < 0.05). CONCLUSION: According to our finding, EDIP was associated with obesity, high prevalence of dyslipidemia and cardio-metabolic risk factors. Moreover, EDIP was in an inverse association with dietary antioxidant quality score and dietary phytochemical index. Therefore, EDIP could be assumed as a precise tool for estimating the CVD related risk factors among patients candidate for CABG.
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spelling pubmed-62967112018-12-28 Empirically developed dietary inflammatory potential (EDIP) in patients candidate for coronary artery bypass grafting surgery (CABG): Association with metabolic parameters, dietary antioxidant quality score and dietary phytochemical index Abbasalizad Farhangi, Mahdieh Najafi, Mahdi PLoS One Research Article AIMS: It has been suggested that empirically developed dietary inflammatory potential (EDIP) is a diagnostic tool for assessment of inflammatory potential of diet in prediction of risk factors related to chronic disease. In the current work, we examined the association between EDIP with cardio-metabolic risk factors, dietary antioxidant quality score (DAQs), dietary phytochemical index (DPI) and Mediterranean dietary quality index (MEDQI) in patients candidate for CABG. MATERIALS AND METHODS: In the current cross-sectional study, the data obtained from Tehran- Heart Center-Coronary Outcome Measurement (THC-COM) study from 454 patients candidate for the CABG were used. Laboratory measurements including hemoglobin (Hb)-A1C, serum lipids, creatinine, blood urea nitrogen (BUN), hematocrit, Lp(a), telomerase activity, serum vitamin D and c-reactive protein (CRP) were measured with commercial laboratory methods. Dietary indices were measured according to the data obtained from with semi-quantitative FFQ. RESULTS: In the current work, patients in top quintile of EDIP had higher BMI and higher prevalence of hyperlipidemia compared with patients in lowest quintile (BMI: 28.08 ±3.68 vs 26.69 ± 3.67 and hyperlipidemia: 77.8 vs 65.5%; P < 0.05). Moreover, lower EDIP scores were accompanied with higher vitamin E (0.48 vs 0.4) and total dietary antioxidant scores (4.40 VS 4.28), higher dietary phytochemical scores (69.79 vs 58.29) and lower dietary Mediterranean quality scores (P < 0.05 and P < 0.01 respectively). In male patients, being at highest quintiles of EDIP make patients 2–5% more likely to have higher concentrations of serum cholesterol, BUN and Lp (a), and 6 to 8 times more likely to have higher creatinine and 66% more likely to have lower albumin concentrations compared with male patients in lowest quintiles. In female patients, lower HCT, higher creatinine, higher CRP concentrations and higher telomerase activity were also achieved by higher EDIP scores (P < 0.05). CONCLUSION: According to our finding, EDIP was associated with obesity, high prevalence of dyslipidemia and cardio-metabolic risk factors. Moreover, EDIP was in an inverse association with dietary antioxidant quality score and dietary phytochemical index. Therefore, EDIP could be assumed as a precise tool for estimating the CVD related risk factors among patients candidate for CABG. Public Library of Science 2018-12-17 /pmc/articles/PMC6296711/ /pubmed/30557399 http://dx.doi.org/10.1371/journal.pone.0208711 Text en © 2018 Abbasalizad Farhangi, Najafi http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Abbasalizad Farhangi, Mahdieh
Najafi, Mahdi
Empirically developed dietary inflammatory potential (EDIP) in patients candidate for coronary artery bypass grafting surgery (CABG): Association with metabolic parameters, dietary antioxidant quality score and dietary phytochemical index
title Empirically developed dietary inflammatory potential (EDIP) in patients candidate for coronary artery bypass grafting surgery (CABG): Association with metabolic parameters, dietary antioxidant quality score and dietary phytochemical index
title_full Empirically developed dietary inflammatory potential (EDIP) in patients candidate for coronary artery bypass grafting surgery (CABG): Association with metabolic parameters, dietary antioxidant quality score and dietary phytochemical index
title_fullStr Empirically developed dietary inflammatory potential (EDIP) in patients candidate for coronary artery bypass grafting surgery (CABG): Association with metabolic parameters, dietary antioxidant quality score and dietary phytochemical index
title_full_unstemmed Empirically developed dietary inflammatory potential (EDIP) in patients candidate for coronary artery bypass grafting surgery (CABG): Association with metabolic parameters, dietary antioxidant quality score and dietary phytochemical index
title_short Empirically developed dietary inflammatory potential (EDIP) in patients candidate for coronary artery bypass grafting surgery (CABG): Association with metabolic parameters, dietary antioxidant quality score and dietary phytochemical index
title_sort empirically developed dietary inflammatory potential (edip) in patients candidate for coronary artery bypass grafting surgery (cabg): association with metabolic parameters, dietary antioxidant quality score and dietary phytochemical index
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296711/
https://www.ncbi.nlm.nih.gov/pubmed/30557399
http://dx.doi.org/10.1371/journal.pone.0208711
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