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Comparing the Effects of Low-Protein and High-Carbohydrate Diets and Caloric Restriction on Brain Aging in Mice
Calorie restriction (CR) increases lifespan and improves brain health in mice. Ad libitum low-protein, highcarbohydrate (LPHC) diets also extend lifespan, but it is not known whether they are beneficial for brain health. We compared hippocampus biology and memory in mice subjected to 20% CR or provi...
Autores principales: | Wahl, Devin, Solon-Biet, Samantha M., Wang, Qiao-Ping, Wali, Jibran A., Pulpitel, Tamara, Clark, Ximonie, Raubenheimer, David, Senior, Alistair M., Sinclair, David A., Cooney, Gregory J., de Cabo, Rafael, Cogger, Victoria C., Simpson, Stephen J., Le Couteur, David G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296764/ https://www.ncbi.nlm.nih.gov/pubmed/30463018 http://dx.doi.org/10.1016/j.celrep.2018.10.070 |
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