Polychlorinated biphenyls reduce the kinematics contractile properties of embryonic stem cells-derived cardiomyocytes by disrupting their intracellular Ca(2+) dynamics

Persistent organic pollutants are a group of chemicals that include polychlorinated biphenyls (PCBs). PCBs exposure during adult life increases incidence and severity of cardiomyopathies, whereas in utero exposure determines congenital heart defects. Being fat-soluble, PCBs are passed to newborns th...

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Detalles Bibliográficos
Autores principales: Rebuzzini, Paola, Zuccolo, Estella, Civello, Cinzia, Fassina, Lorenzo, Arechaga, Juan, Izquierdo, Amaia, Faris, Pawan, Zuccotti, Maurizio, Moccia, Francesco, Garagna, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297156/
https://www.ncbi.nlm.nih.gov/pubmed/30559452
http://dx.doi.org/10.1038/s41598-018-36333-z

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