SOX9 regulated matrix proteins are increased in patients serum and correlate with severity of liver fibrosis

Extracellular matrix (ECM) deposition and resultant scar play a major role in the pathogenesis and progression of liver fibrosis. Identifying core regulators of ECM deposition may lead to urgently needed diagnostic and therapetic strategies for the disease. The transcription factor Sex determining r...

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Detalles Bibliográficos
Autores principales: Athwal, Varinder S., Pritchett, James, Martin, Katherine, Llewellyn, Jessica, Scott, Jennifer, Harvey, Emma, Zaitoun, Abed M., Mullan, Aoibheann F., Zeef, Leo A. H., Friedman, Scott L., Irving, William L., Hanley, Neil A., Guha, Indra N., Piper Hanley, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297163/
https://www.ncbi.nlm.nih.gov/pubmed/30559459
http://dx.doi.org/10.1038/s41598-018-36037-4

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