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Influence of the IGFBP3-202A/C Gene Polymorphism on Clinical Features and Surgery Outcome in Acromegalic Patients

Purpose: Excess growth hormone (GH) secretion in acromegaly patients results in increased levels of IGF-1 expression, which causes the clinical manifestations of acromegaly. IGF-1 levels are attenuated by IGFBP3, and a polymorphism in the promoter of IGFBP3 is known to affect the circulating level o...

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Detalles Bibliográficos
Autores principales:	Gao, Ming, Zhu, Bin, Li, Ping, Zhang, Guojun, Chen, Kelin, Lv, Hong, Ma, Ruimin, Zhang, Limin, Fan, Yubo, Kang, Xixiong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297192/ https://www.ncbi.nlm.nih.gov/pubmed/30619084 http://dx.doi.org/10.3389/fendo.2018.00751

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