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JunB regulates homeostasis and suppressive functions of effector regulatory T cells

Foxp3-expressing CD4(+) regulatory T (Treg) cells need to differentiate into effector Treg (eTreg) cells to maintain immune homeostasis. T-cell receptor (TCR)-dependent induction of the transcription factor IRF4 is essential for eTreg differentiation, but how IRF4 activity is regulated in Treg cells...

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Detalles Bibliográficos
Autores principales:	Koizumi, Shin-ichi, Sasaki, Daiki, Hsieh, Tsung-Han, Taira, Naoyuki, Arakaki, Nana, Yamasaki, Shinichi, Wang, Ke, Sarkar, Shukla, Shirahata, Hiroki, Miyagi, Mio, Ishikawa, Hiroki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297218/ https://www.ncbi.nlm.nih.gov/pubmed/30559442 http://dx.doi.org/10.1038/s41467-018-07735-4

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