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Routes of Zika virus dissemination in the testis and epididymis of immunodeficient mice

Sexual transmission and persistence of Zika virus (ZIKV) in the male reproductive tract (MRT) poses new challenges for controlling virus outbreaks and developing live-attenuated vaccines. To elucidate routes of ZIKV dissemination in the MRT, we here generate microRNA-targeted ZIKV clones that lose t...

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Detalles Bibliográficos
Autores principales: Tsetsarkin, Konstantin A., Maximova, Olga A., Liu, Guangping, Kenney, Heather, Teterina, Natalia, Bloom, Marshall E., Grabowski, Jeffrey M., Mlera, Luwanika, Nagata, Bianca M., Moore, Ian, Martens, Craig, Amaro-Carambot, Emerito, Lamirande, Elaine W., Whitehead, Stephen S., Pletnev, Alexander G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297220/
https://www.ncbi.nlm.nih.gov/pubmed/30559387
http://dx.doi.org/10.1038/s41467-018-07782-x