aPKC controls endothelial growth by modulating c-Myc via FoxO1 DNA-binding ability

Strict regulation of proliferation is vital for development, whereas unregulated cell proliferation is a fundamental characteristic of cancer. The polarity protein atypical protein kinase C lambda/iota (aPKCλ) is associated with cell proliferation through unknown mechanisms. In endothelial cells, su...

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Detalles Bibliográficos
Autores principales: Riddell, Meghan, Nakayama, Akiko, Hikita, Takao, Mirzapourshafiyi, Fatemeh, Kawamura, Takuji, Pasha, Ayesha, Li, Mengnan, Masuzawa, Mikio, Looso, Mario, Steinbacher, Tim, Ebnet, Klaus, Potente, Michael, Hirose, Tomonori, Ohno, Shigeo, Fleming, Ingrid, Gattenlöhner, Stefan, Aung, Phyu P., Phung, Thuy, Yamasaki, Osamu, Yanagi, Teruki, Umemura, Hiroshi, Nakayama, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297234/
https://www.ncbi.nlm.nih.gov/pubmed/30559384
http://dx.doi.org/10.1038/s41467-018-07739-0

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