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Calmodulinopathy: Functional Effects of CALM Mutations and Their Relationship With Clinical Phenotypes
In spite of the widespread role of calmodulin (CaM) in cellular signaling, CaM mutations lead specifically to cardiac manifestations, characterized by remarkable electrical instability and a high incidence of sudden death at young age. Penetrance of the mutations is surprisingly high, thus postulati...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297375/ https://www.ncbi.nlm.nih.gov/pubmed/30619883 http://dx.doi.org/10.3389/fcvm.2018.00176 |