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Inactivation of Cyclin-Dependent Kinase 5 in Hair Cells Causes Hearing Loss in Mice

Cyclin-dependent kinase 5 (CDK5) is abundantly expressed in post-mitotic cells including neurons. It is involved in multiple cellular events, such as cytoskeletal dynamics, signaling cascades, gene expression, and cell survival, et al. Dysfunction of CDK5 has been associated with a number of neurolo...

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Detalles Bibliográficos
Autores principales: Zhai, Xiaoyan, Liu, Chengcheng, Zhao, Bin, Wang, Yanfei, Xu, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297389/
https://www.ncbi.nlm.nih.gov/pubmed/30618612
http://dx.doi.org/10.3389/fnmol.2018.00461