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Inactivation of Cyclin-Dependent Kinase 5 in Hair Cells Causes Hearing Loss in Mice
Cyclin-dependent kinase 5 (CDK5) is abundantly expressed in post-mitotic cells including neurons. It is involved in multiple cellular events, such as cytoskeletal dynamics, signaling cascades, gene expression, and cell survival, et al. Dysfunction of CDK5 has been associated with a number of neurolo...
Autores principales: | Zhai, Xiaoyan, Liu, Chengcheng, Zhao, Bin, Wang, Yanfei, Xu, Zhigang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297389/ https://www.ncbi.nlm.nih.gov/pubmed/30618612 http://dx.doi.org/10.3389/fnmol.2018.00461 |
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