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Temporal Integrative Analysis of mRNA and microRNAs Expression Profiles and Epigenetic Alterations in Female SAMP8, a Model of Age-Related Cognitive Decline
A growing body of research shows that epigenetic mechanisms are critically involved in normal and pathological aging. The Senescence-Accelerated Mouse Prone 8 (SAMP8) can be considered a useful tool to better understand the dynamics of the global epigenetic landscape during the aging process since i...
Autores principales: | Cosín-Tomás, Marta, Álvarez-López, María Jesús, Companys-Alemany, Júlia, Kaliman, Perla, González-Castillo, Celia, Ortuño-Sahagún, Daniel, Pallàs, Mercè, Griñán-Ferré, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297390/ https://www.ncbi.nlm.nih.gov/pubmed/30619445 http://dx.doi.org/10.3389/fgene.2018.00596 |
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