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Toxicological Analysis of Insects on the Corpse: A Valuable Source of Information in Forensic Investigations

BACKGROUND: Entomotoxicology as a subset of forensic entomology can be used by analysis of carcass feeding insects to detecting of drugs or toxins, as well as the cause and manner of death in cases of ante-mortem drugs intoxication. Morphine is one of the deacetylate metabolites of heroin. The aim o...

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Autores principales: Salimi, Mojtaba, Rassi, Yavar, Chatrabgoun, Omid, Kamali, Artin, Oshaghi, Mohammad Ali, Shiri-Ghaleh, Vida, Moradi, Mehrdad, Rafizadeh, Sayena, Akbarzadeh, Kameran, Parkhideh, Seyedeh Zahra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297721/
https://www.ncbi.nlm.nih.gov/pubmed/30584545
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author Salimi, Mojtaba
Rassi, Yavar
Chatrabgoun, Omid
Kamali, Artin
Oshaghi, Mohammad Ali
Shiri-Ghaleh, Vida
Moradi, Mehrdad
Rafizadeh, Sayena
Akbarzadeh, Kameran
Parkhideh, Seyedeh Zahra
author_facet Salimi, Mojtaba
Rassi, Yavar
Chatrabgoun, Omid
Kamali, Artin
Oshaghi, Mohammad Ali
Shiri-Ghaleh, Vida
Moradi, Mehrdad
Rafizadeh, Sayena
Akbarzadeh, Kameran
Parkhideh, Seyedeh Zahra
author_sort Salimi, Mojtaba
collection PubMed
description BACKGROUND: Entomotoxicology as a subset of forensic entomology can be used by analysis of carcass feeding insects to detecting of drugs or toxins, as well as the cause and manner of death in cases of ante-mortem drugs intoxication. Morphine is one of the deacetylate metabolites of heroin. The aim of this study was to determine the presence and quantity of morphine in insects on the carcass and compare them with decomposing carcass. METHODS: Field of this study was in Chalabeh District and toxicological tests were carried out at the Department of Forensic Toxicology, Legal Medicine Center, Kermanshah, Iran in 2017. Morphine was inoculated into live rabbit as experimental model at concentrations of 12.5, 25, 50mg/ml, similar to those normally encountered in human overdoses, then quality and quantity of morphine were determined in insects such as Chrysomya albiceps (as the first wave of insect succession on human cadavers) fed on carcass. RESULTS: Quantitative assessment at larvae showed that morphine was detected in all larvae (feeding and post feeding stage) fed on tissues from carcasses administered morphine, except for post-feeding larvae from R1 which received 12.5mg/ml dosage of morphine. CONCLUSION: Necrophagous insects are an indicator on the scene of crime and a potential source of information about the antemortem situation. Detection of drug in insects which is actually a reflection of the cause of death is possible.
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spelling pubmed-62977212018-12-24 Toxicological Analysis of Insects on the Corpse: A Valuable Source of Information in Forensic Investigations Salimi, Mojtaba Rassi, Yavar Chatrabgoun, Omid Kamali, Artin Oshaghi, Mohammad Ali Shiri-Ghaleh, Vida Moradi, Mehrdad Rafizadeh, Sayena Akbarzadeh, Kameran Parkhideh, Seyedeh Zahra J Arthropod Borne Dis Original Article BACKGROUND: Entomotoxicology as a subset of forensic entomology can be used by analysis of carcass feeding insects to detecting of drugs or toxins, as well as the cause and manner of death in cases of ante-mortem drugs intoxication. Morphine is one of the deacetylate metabolites of heroin. The aim of this study was to determine the presence and quantity of morphine in insects on the carcass and compare them with decomposing carcass. METHODS: Field of this study was in Chalabeh District and toxicological tests were carried out at the Department of Forensic Toxicology, Legal Medicine Center, Kermanshah, Iran in 2017. Morphine was inoculated into live rabbit as experimental model at concentrations of 12.5, 25, 50mg/ml, similar to those normally encountered in human overdoses, then quality and quantity of morphine were determined in insects such as Chrysomya albiceps (as the first wave of insect succession on human cadavers) fed on carcass. RESULTS: Quantitative assessment at larvae showed that morphine was detected in all larvae (feeding and post feeding stage) fed on tissues from carcasses administered morphine, except for post-feeding larvae from R1 which received 12.5mg/ml dosage of morphine. CONCLUSION: Necrophagous insects are an indicator on the scene of crime and a potential source of information about the antemortem situation. Detection of drug in insects which is actually a reflection of the cause of death is possible. Tehran University of Medical Sciences 2018-09-30 /pmc/articles/PMC6297721/ /pubmed/30584545 Text en Copyright© Iranian Society of Medical Entomology & Tehran University of Medical Sciences http://creativecommons.org/licenses/by/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.
spellingShingle Original Article
Salimi, Mojtaba
Rassi, Yavar
Chatrabgoun, Omid
Kamali, Artin
Oshaghi, Mohammad Ali
Shiri-Ghaleh, Vida
Moradi, Mehrdad
Rafizadeh, Sayena
Akbarzadeh, Kameran
Parkhideh, Seyedeh Zahra
Toxicological Analysis of Insects on the Corpse: A Valuable Source of Information in Forensic Investigations
title Toxicological Analysis of Insects on the Corpse: A Valuable Source of Information in Forensic Investigations
title_full Toxicological Analysis of Insects on the Corpse: A Valuable Source of Information in Forensic Investigations
title_fullStr Toxicological Analysis of Insects on the Corpse: A Valuable Source of Information in Forensic Investigations
title_full_unstemmed Toxicological Analysis of Insects on the Corpse: A Valuable Source of Information in Forensic Investigations
title_short Toxicological Analysis of Insects on the Corpse: A Valuable Source of Information in Forensic Investigations
title_sort toxicological analysis of insects on the corpse: a valuable source of information in forensic investigations
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297721/
https://www.ncbi.nlm.nih.gov/pubmed/30584545
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