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Ig-Like Transcript 2 (ILT2) Blockade and Lenalidomide Restore NK Cell Function in Chronic Lymphocytic Leukemia
One of the cardinal features of chronic lymphocytic leukemia (CLL) is its association with a profound immunosuppression. NK cell function is markedly impaired in CLL patients, who show a significant dysregulation of the expression of activating and inhibitory receptors. Here, we analyzed the role of...
Autores principales: | Villa-Álvarez, Mónica, Sordo-Bahamonde, Christian, Lorenzo-Herrero, Seila, Gonzalez-Rodriguez, Ana P., Payer, Angel R., Gonzalez-Garcia, Esther, Villa-Álvarez, María C., López-Soto, Alejandro, Gonzalez, Segundo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297751/ https://www.ncbi.nlm.nih.gov/pubmed/30619281 http://dx.doi.org/10.3389/fimmu.2018.02917 |
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