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P4HB knockdown induces human HT29 colon cancer cell apoptosis through the generation of reactive oxygen species and inactivation of STAT3 signaling

Colon cancer is the second most lethal malignancy worldwide. A better understanding of colon cancer at the molecular level may increase overall survival rates. Previous studies have indicated that prolyl 4-hydroxylase, β polypeptide (P4HB) is associated with tumorigenesis in colon cancer; however, i...

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Detalles Bibliográficos
Autores principales:	Zhou, Ying, Yang, Jing, Zhang, Qilin, Xu, Qihua, Lu, Lihua, Wang, Jiening, Xia, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297753/ https://www.ncbi.nlm.nih.gov/pubmed/30431122 http://dx.doi.org/10.3892/mmr.2018.9660

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