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Cabazitaxel liposomes with aptamer modification enhance tumor-targeting efficacy in nude mice

The present study investigated the feasibility of improving the tumor-targeting efficacy and decreasing the toxicity of liposomal cabazitaxel (Cab) with aptamer modification. The process involved preparing aptamer (TLS1c)-modified liposomes and studying the behavior of the liposomes in vitro and in...

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Detalles Bibliográficos
Autores principales: Cheng, Yuzhu, Ou, Zhanlun, Li, Qingguo, Yang, Juan, Hu, Min, Zhou, Yubin, Zhuang, Xiaodong, Zhang, Zhenyu Jason, Guan, Shixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297770/
https://www.ncbi.nlm.nih.gov/pubmed/30483775
http://dx.doi.org/10.3892/mmr.2018.9689