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MEK inhibition prevents TGF-β1-induced myofibroblast transdifferentiation in human tenon fibroblasts

Subconjunctival fibrosis represents the primary cause of postoperative failure of trabeculectomy, and at present there is a lack of effective intervention strategies. The present study aimed to investigate the effect of the mitogen-activated protein kinase kinase (MEK) inhibitor U0126 on human tenon...

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Detalles Bibliográficos
Autores principales:	Wen, Jiamin, Lin, Xianchai, Gao, Wuyou, Qu, Bo, Ling, Yunlan, Liu, Rongjiao, Yu, Minbin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297771/ https://www.ncbi.nlm.nih.gov/pubmed/30483803 http://dx.doi.org/10.3892/mmr.2018.9673

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