DNA-Mediated Interferon Signature Induction by SLE Serum Occurs in Monocytes Through Two Pathways: A Mechanism to Inhibit Both Pathways

A primary mechanism for activation of innate immunity is recognition of damage or pathogen associated molecular patterns by pattern recognition receptors (PRRs). Nucleic acid is a damage associated molecular pattern molecule that when internalized into a monocyte and recognized by intracellular nucl...

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Detalles Bibliográficos
Autores principales: Porat, Amit, Giat, Eitan, Kowal, Czeslawa, He, Mingzhu, Son, Myoungsun, Latz, Eicke, Ben-Zvi, Ilan, Al-Abed, Yousef, Diamond, Betty
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297782/
https://www.ncbi.nlm.nih.gov/pubmed/30619247
http://dx.doi.org/10.3389/fimmu.2018.02824

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