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Progranulin protects the mouse retina under hypoxic conditions via inhibition of the Toll-like receptor-4-NADPH oxidase 4 signaling pathway

To investigate the function of progranulin on the retina under hypoxic conditions, 8-week-old C57BL/6 mice were divided into normal condition and hypoxic condition groups (n=24 mice/group). The hypoxia model was established through intravitreal injection of 9 mM cobalt chloride. Subsequently, 10 mM...

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Detalles Bibliográficos
Autores principales: You, Zhi-Peng, Yu, Meng-Jia, Zhang, Yu-Lan, Shi, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297797/
https://www.ncbi.nlm.nih.gov/pubmed/30431085
http://dx.doi.org/10.3892/mmr.2018.9634