Plasma Cell–Free DNA Next-Generation Sequencing to Diagnose and Monitor Infections in Allogeneic Hematopoietic Stem Cell Transplant Patients

Allogeneic hematopoietic stem cell transplant patients are at risk for common and atypical infections. Superior diagnostics can decrease infection-related morbidity and mortality. A novel plasma cell–free DNA next-generation sequencing test detected an uncommon presentation of Chlamydia trachomatis...

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Autores principales: Fung, Monica, Zompi, Simona, Seng, Hon, Hollemon, Desiree, Parham, Adama, Hong, David K, Bercovici, Sivan, Dolan, Estelle, Lien, Kathy, Teraoka, Justin, Logan, Aaron C, Chin-Hong, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297859/
https://www.ncbi.nlm.nih.gov/pubmed/30581881
http://dx.doi.org/10.1093/ofid/ofy301
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author Fung, Monica
Zompi, Simona
Seng, Hon
Hollemon, Desiree
Parham, Adama
Hong, David K
Bercovici, Sivan
Dolan, Estelle
Lien, Kathy
Teraoka, Justin
Logan, Aaron C
Chin-Hong, Peter
author_facet Fung, Monica
Zompi, Simona
Seng, Hon
Hollemon, Desiree
Parham, Adama
Hong, David K
Bercovici, Sivan
Dolan, Estelle
Lien, Kathy
Teraoka, Justin
Logan, Aaron C
Chin-Hong, Peter
author_sort Fung, Monica
collection PubMed
description Allogeneic hematopoietic stem cell transplant patients are at risk for common and atypical infections. Superior diagnostics can decrease infection-related morbidity and mortality. A novel plasma cell–free DNA next-generation sequencing test detected an uncommon presentation of Chlamydia trachomatis and recurrent and metastatic complications of Staphylococcus aureus bacteremia before standard microbiology.
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spelling pubmed-62978592018-12-21 Plasma Cell–Free DNA Next-Generation Sequencing to Diagnose and Monitor Infections in Allogeneic Hematopoietic Stem Cell Transplant Patients Fung, Monica Zompi, Simona Seng, Hon Hollemon, Desiree Parham, Adama Hong, David K Bercovici, Sivan Dolan, Estelle Lien, Kathy Teraoka, Justin Logan, Aaron C Chin-Hong, Peter Open Forum Infect Dis Brief Report Allogeneic hematopoietic stem cell transplant patients are at risk for common and atypical infections. Superior diagnostics can decrease infection-related morbidity and mortality. A novel plasma cell–free DNA next-generation sequencing test detected an uncommon presentation of Chlamydia trachomatis and recurrent and metastatic complications of Staphylococcus aureus bacteremia before standard microbiology. Oxford University Press 2018-11-16 /pmc/articles/PMC6297859/ /pubmed/30581881 http://dx.doi.org/10.1093/ofid/ofy301 Text en © The Author(s) 2018. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Report
Fung, Monica
Zompi, Simona
Seng, Hon
Hollemon, Desiree
Parham, Adama
Hong, David K
Bercovici, Sivan
Dolan, Estelle
Lien, Kathy
Teraoka, Justin
Logan, Aaron C
Chin-Hong, Peter
Plasma Cell–Free DNA Next-Generation Sequencing to Diagnose and Monitor Infections in Allogeneic Hematopoietic Stem Cell Transplant Patients
title Plasma Cell–Free DNA Next-Generation Sequencing to Diagnose and Monitor Infections in Allogeneic Hematopoietic Stem Cell Transplant Patients
title_full Plasma Cell–Free DNA Next-Generation Sequencing to Diagnose and Monitor Infections in Allogeneic Hematopoietic Stem Cell Transplant Patients
title_fullStr Plasma Cell–Free DNA Next-Generation Sequencing to Diagnose and Monitor Infections in Allogeneic Hematopoietic Stem Cell Transplant Patients
title_full_unstemmed Plasma Cell–Free DNA Next-Generation Sequencing to Diagnose and Monitor Infections in Allogeneic Hematopoietic Stem Cell Transplant Patients
title_short Plasma Cell–Free DNA Next-Generation Sequencing to Diagnose and Monitor Infections in Allogeneic Hematopoietic Stem Cell Transplant Patients
title_sort plasma cell–free dna next-generation sequencing to diagnose and monitor infections in allogeneic hematopoietic stem cell transplant patients
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297859/
https://www.ncbi.nlm.nih.gov/pubmed/30581881
http://dx.doi.org/10.1093/ofid/ofy301
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