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Simple statistical identification and removal of contaminant sequences in marker-gene and metagenomics data
BACKGROUND: The accuracy of microbial community surveys based on marker-gene and metagenomic sequencing (MGS) suffers from the presence of contaminants—DNA sequences not truly present in the sample. Contaminants come from various sources, including reagents. Appropriate laboratory practices can redu...
Autores principales: | Davis, Nicole M., Proctor, Diana M., Holmes, Susan P., Relman, David A., Callahan, Benjamin J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298009/ https://www.ncbi.nlm.nih.gov/pubmed/30558668 http://dx.doi.org/10.1186/s40168-018-0605-2 |
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