Cargando…
The CD4(−)CD8(−) MAIT cell subpopulation is a functionally distinct subset developmentally related to the main CD8(+) MAIT cell pool
Mucosa-associated invariant T (MAIT) cells are unconventional innate-like T cells that recognize microbial riboflavin metabolites presented by the MHC class I-like protein MR1. Human MAIT cells predominantly express the CD8α coreceptor (CD8(+)), with a smaller subset lacking both CD4 and CD8 (double...
Autores principales: | Dias, Joana, Boulouis, Caroline, Gorin, Jean-Baptiste, van den Biggelaar, Robin H. G. A., Lal, Kerri G., Gibbs, Anna, Loh, Liyen, Gulam, Muhammad Yaaseen, Sia, Wan Rong, Bari, Sudipto, Hwang, William Y. K., Nixon, Douglas F., Nguyen, Son, Betts, Michael R., Buggert, Marcus, Eller, Michael A., Broliden, Kristina, Tjernlund, Annelie, Sandberg, Johan K., Leeansyah, Edwin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298106/ https://www.ncbi.nlm.nih.gov/pubmed/30442667 http://dx.doi.org/10.1073/pnas.1812273115 |
Ejemplares similares
-
MAIT Cells Are Major Contributors to the Cytokine Response in Group A Streptococcal Toxic Shock Syndrome
por: Emgård, Johanna, et al.
Publicado: (2019) -
Acquisition of innate-like microbial reactivity in mucosal tissues during human fetal MAIT-cell development
por: Leeansyah, Edwin, et al.
Publicado: (2014) -
MAIT cells reside in the female genital mucosa and are biased towards IL-17 and IL-22 production in response to bacterial stimulation
por: Gibbs, Anna, et al.
Publicado: (2016) -
MAIT cells boost adenovirus-induced CD8(+) T cells
por: Flemming, Alexandra
Publicado: (2021) -
Select sequencing of clonally expanded CD8(+) T cells reveals limits to clonal expansion
por: Huang, Huang, et al.
Publicado: (2019)