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The Effects of Graded Levels of Calorie Restriction: XIII. Global Metabolomics Screen Reveals Graded Changes in Circulating Amino Acids, Vitamins, and Bile Acids in the Plasma of C57BL/6 Mice

Calorie restriction (CR) remains the most robust intervention to extend life span and improve health span. Using a global mass spectrometry–based metabolomics approach, we identified metabolites that were significantly differentially expressed in the plasma of C57BL/6 mice, fed graded levels of calo...

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Detalles Bibliográficos
Autores principales: Green, Cara L, Soltow, Quinlyn A, Mitchell, Sharon E, Derous, Davina, Wang, Yingchun, Chen, Luonan, Han, Jing-Dong J, Promislow, Daniel E L, Lusseau, David, Douglas, Alex, Jones, Dean P, Speakman, John R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298180/
https://www.ncbi.nlm.nih.gov/pubmed/29718123
http://dx.doi.org/10.1093/gerona/gly058