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Tracking the Epigenetic Clock Across the Human Life Course: A Meta-analysis of Longitudinal Cohort Data

BACKGROUND: Epigenetic clocks based on DNA methylation yield high correlations with chronological age in cross-sectional data. Due to a paucity of longitudinal data, it is not known how Δ(age) (epigenetic age – chronological age) changes over time or if it remains constant from childhood to old age....

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Detalles Bibliográficos
Autores principales: Marioni, Riccardo E, Suderman, Matthew, Chen, Brian H, Horvath, Steve, Bandinelli, Stefania, Morris, Tiffany, Beck, Stephan, Ferrucci, Luigi, Pedersen, Nancy L, Relton, Caroline L, Deary, Ian J, Hägg, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298183/
https://www.ncbi.nlm.nih.gov/pubmed/29718110
http://dx.doi.org/10.1093/gerona/gly060