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A randomized, single ascending dose study of intravenous BIIB092 in healthy participants

INTRODUCTION: Extracellular tau is hypothesized to mediate the onset and progression of tauopathies, including Alzheimer's disease, progressive supranuclear palsy, and a subset of frontotemporal lobar degenerations. A putative strategy for treating these disorders is to reduce extracellular tau...

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Detalles Bibliográficos
Autores principales:	Qureshi, Irfan A., Tirucherai, Giridhar, Ahlijanian, Michael K., Kolaitis, Gerry, Bechtold, Clifford, Grundman, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Featured Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298197/ https://www.ncbi.nlm.nih.gov/pubmed/30581980 http://dx.doi.org/10.1016/j.trci.2018.10.007

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