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A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway

Tumor Necrosis Factor (TNF) has a crucial role in inflammation, cell proliferation and cell death. Dysregulation of TNF receptor 1 (TNFR1)-induced Nuclear Factor-kappa B (NF-κB) signaling leads to chronic inflammation and is associated with several human inflammatory pathologies. Hence, TNF neutrali...

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Detalles Bibliográficos
Autores principales: Van Quickelberghe, Emmy, De Sutter, Delphine, van Loo, Geert, Eyckerman, Sven, Gevaert, Kris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298254/
https://www.ncbi.nlm.nih.gov/pubmed/30561431
http://dx.doi.org/10.1038/sdata.2018.289

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