Familial Intracranial Aneurysms in Saudi Arabia: What Do We Need To Do?

Aneurysmal subarachnoid hemorrhage (SAH) is a devastating event with significant morbidity and mortality. The incidence of SAH might be influenced by environmental factors but genetic predisposition is evolving as an important effector in the risk of development of intracranial aneurysms and rupture...

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Autores principales: Al-Jehani, Hosam, Yamani, Mahmoud, Orz, Yasser, Shiekh, Bassem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298339/
https://www.ncbi.nlm.nih.gov/pubmed/30787721
http://dx.doi.org/10.4103/1658-631X.188252
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author Al-Jehani, Hosam
Yamani, Mahmoud
Orz, Yasser
Shiekh, Bassem
author_facet Al-Jehani, Hosam
Yamani, Mahmoud
Orz, Yasser
Shiekh, Bassem
author_sort Al-Jehani, Hosam
collection PubMed
description Aneurysmal subarachnoid hemorrhage (SAH) is a devastating event with significant morbidity and mortality. The incidence of SAH might be influenced by environmental factors but genetic predisposition is evolving as an important effector in the risk of development of intracranial aneurysms and rupture of aneurysms. This requires strategies for effective screening of family members at risk of developing such a phenotype, in order to deliver preventive treatment to these target lesions. We discuss the potential for implementing these strategies in the Saudi Arabian health system and the future implications on our care for such a vulnerable group of subjects.
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spelling pubmed-62983392019-02-20 Familial Intracranial Aneurysms in Saudi Arabia: What Do We Need To Do? Al-Jehani, Hosam Yamani, Mahmoud Orz, Yasser Shiekh, Bassem Saudi J Med Med Sci Review Article Aneurysmal subarachnoid hemorrhage (SAH) is a devastating event with significant morbidity and mortality. The incidence of SAH might be influenced by environmental factors but genetic predisposition is evolving as an important effector in the risk of development of intracranial aneurysms and rupture of aneurysms. This requires strategies for effective screening of family members at risk of developing such a phenotype, in order to deliver preventive treatment to these target lesions. We discuss the potential for implementing these strategies in the Saudi Arabian health system and the future implications on our care for such a vulnerable group of subjects. Medknow Publications & Media Pvt Ltd 2016 2016-08-11 /pmc/articles/PMC6298339/ /pubmed/30787721 http://dx.doi.org/10.4103/1658-631X.188252 Text en Copyright: © 2016 Saudi Journal of Medicine & Medical Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Review Article
Al-Jehani, Hosam
Yamani, Mahmoud
Orz, Yasser
Shiekh, Bassem
Familial Intracranial Aneurysms in Saudi Arabia: What Do We Need To Do?
title Familial Intracranial Aneurysms in Saudi Arabia: What Do We Need To Do?
title_full Familial Intracranial Aneurysms in Saudi Arabia: What Do We Need To Do?
title_fullStr Familial Intracranial Aneurysms in Saudi Arabia: What Do We Need To Do?
title_full_unstemmed Familial Intracranial Aneurysms in Saudi Arabia: What Do We Need To Do?
title_short Familial Intracranial Aneurysms in Saudi Arabia: What Do We Need To Do?
title_sort familial intracranial aneurysms in saudi arabia: what do we need to do?
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298339/
https://www.ncbi.nlm.nih.gov/pubmed/30787721
http://dx.doi.org/10.4103/1658-631X.188252
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AT orzyasser familialintracranialaneurysmsinsaudiarabiawhatdoweneedtodo
AT shiekhbassem familialintracranialaneurysmsinsaudiarabiawhatdoweneedtodo

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